Vaginal microbicides may benefit men more than women, study shows
Researchers also say clinical-trial design may mask risk of drug resistance
Vaginal microbicides currently in clinical trials may be the only weapon that will protect women against infection from HIV. Yet, under likely circumstances, these microbicides may be of more benefit to men than women, according to a new UCLA AIDS Institute study.
The study, which used novel mathematical models to simulate clinical trials and population-level transmission of HIV, appears July 7 in the online issue of Proceedings of the National Academy of Sciences.