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Investigadores usan cryotomografía de electrones para obtener la primer imagen 3D de la arquitectura de pared celular bacteriana

Nov 17, 2008 By Admin2

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Caltech Researchers Use Electron Cryotomography to Get First 3-D Glimpse of Bacterial Cell-Wall Architecture
Findings represent important advances in both biology and imaging technology

PASADENA, Calif.--The bacterial cell wall that is the target of potent antibiotics such as penicillin is actually made up of a thin single layer of carbohydrate chains, linked together by peptides, which wrap around the bacterium like a belt around a person, according to research conducted by scientists at the California Institute of Technology (Caltech). This first-ever glimpse of the cell-wall structure in three dimensions was made possible by new high-tech microscopy techniques that enabled the scientists to visualize these biological structures at nanometer scales.

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Una Nueva Clase de Catalizador

Nov 17, 2008 By Admin2

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A new class of catalysts

A new class of exceptionally effective chemical catalysts that promote the powerful olefin metathesis reaction has been discovered by a team of Boston College and MIT scientists, opening up a vast new scientific platform to researchers in medicine, biology and materials.

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Científicos trazan ruta para bloquear enzima clave en la falla cardiaca

Nov 12, 2008 By Admin2

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SCIENTISTS MAP STEPS TO BLOCK KEY ENZYME ACTION IN HEART FAILURE
- S-nitrosylation of cysteine 181mimics action of Viagra-like drugs, which have been shown to rescue failing hearts

Taking a cue from the way drugs like Viagra put the biological brakes on a key enzyme involved in heart failure, scientists at Johns Hopkins have mapped out a key chemical step involved in blocking the enzyme.

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Desenredando la regulación del ADN

Nov 08, 2008 By Admin2

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Untangling DNA regulation
Biologists theorize role for DNA packaging in stem cell development

Anne Trafton, News Office

MIT biologists have discovered that the organization of DNA's packing material plays a critical role in directing stem cells to become different types of adult cells.

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Pequeñas mochilas para las células

Nov 07, 2008 By Ad1

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Tiny backpacks for cells Polymer patches could ferry drugs, assist in cancer diagnosis

Anne Trafton, News Office

MIT engineers have outfitted cells with tiny "backpacks" that could allow them to deliver chemotherapy agents, diagnose tumors or become building blocks for tissue engineering.

Image courtesy / American Chemical Society
This T cell also has a polymer backpack.
The scale bar is 10 micrometers.

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La inmunidad desde el punto de vista de la célula

Nov 04, 2008 By Ad1

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Immunity, from the cell's point of view
Chemical engineers study immune cells in unprecedented detail

Anne Trafton, News Office

MIT engineers have painted the most detailed portrait yet of how single cells from the immune system respond to vaccination.

Photo / Justin Knight/Whitehead Institute

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Remendando los corazones rotos con ingeniería de tejidos

Nov 03, 2008 By Ad1

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Mending broken hearts with tissue engineering
New scaffold approach could also aid engineering of other tissues

Elizabeth A. Thomson, News Office

Broken hearts could one day be mended using a novel scaffold developed by MIT researchers and colleagues.

The idea is that living heart cells or stem cells seeded onto such a scaffold would develop into a patch of cardiac tissue that could be used to treat congenital heart defects, or aid the recovery of tissue damaged by a heart attack. The biodegradable scaffold would be gradually absorbed into the body, leaving behind new tissue.

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